Germinoma

Diagnosis:

Suggested by MRI and confirmed by pathology (brain biopsy/resection)

Clinical features:

Parinaud syndrome
Hydrocephalus

Findings on Investigations:

CT:

  • Pineal region mass
  • Calcified

MRI:

  • Pineal region mass
  • isointense with brain

Pathology:

Histology:

  • Large round blue cells, vesicular nuclei, abundant cytoplasm. With lymphocytic infiltrate.

Immunohistochemisty: PLAP positive

Treatment:

Radiation therapy

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